GABAA receptor: Positive and negative allosteric modulators
نویسندگان
چکیده
منابع مشابه
Novel positive allosteric modulators of GABAA receptors with anesthetic activity
GABAA receptors are the main inhibitory neurotransmitter receptors in the brain and are targets for numerous clinically important drugs such as benzodiazepines, anxiolytics and anesthetics. We previously identified novel ligands of the classical benzodiazepine binding pocket in α1β2γ2 GABAA receptors using an experiment-guided virtual screening (EGVS) method. This screen also identified novel l...
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ژورنال
عنوان ژورنال: Neuropharmacology
سال: 2018
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2018.01.036